Article
Quantitative trait loci for steady-state platelet count in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2004
Cheung Carol C, Martin Ian C A, Zenger Kyall R, Donald Jenny A, Thomson Peter C, Moran Christopher, Buckley Michael F
Abstract excerpt
Platelet count in humans is a strongly genetically regulated trait, with approximately 85% of the interindividual variance in platelet numbers attributable to genetic factors. Inbred mouse strains also have strain-specific platelet count ranges. As part of a project to identify novel factors that regulate platelet count, we identified two inbred mouse strains, CBA/CaH and QSi5, with substantial differences in...
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