Article
Quantitative trait loci analysis for peripheral blood parameters in a (BALB/cW × C57BL/6J-Mpl (hlb219)/J) F(2) mice.
Experimental animals - 1 Jan 2011
Strzalkowska Adriana, Unrug-Bielawska Katarzyna, Bluszcz Aleksandra, Sandowska-Markiewicz Zuzanna, Karaszewska Jadwiga, Pysniak Kazimiera, Gajewska Marta, Wirth-Dzieciolowska Elzbieta
Abstract excerpt
The genetic basis of the peripheral blood cell parameters is not fully elucidated. Thus, it is essential to research the correlation between blood cell counts levels and the genome in laboratory animals and subsequently in humans. In the present study, we examined 288 F(2) mice from a cross between BALB/cW and C57BL/6J-Mpl(hlb219)/J. The C57BL/6J-Mpl (hlb219)/J strain is a mouse model of thrombocytopenia. We...
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