Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element.

doi:10.1007/s00412-007-0132-6

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Article

Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element.

Chromosoma - 1 Apr 2008

Melnikova Larisa, Kostuchenko Margarita, Silicheva Margarita, Georgiev Pavel

Abstract excerpt

There is ample evidence that the enhancers of a promoterless yellow locus in one homologous chromosome can activate the yellow promoter in the other chromosome where the enhancers are inactive or deleted, which is indicative of a high specificity of the enhancer-promoter interaction in yellow. In this paper, we have found that the yellow sequence from -100 to -69 is essential for stimulation of the heterologous...

Topics

Animals
Crosses, Genetic
Drosophila melanogaster
Enhancer Elements, Genetic
Gene Expression Regulation
Insect Proteins
Models, Genetic
Models, Molecular
Mutation
Pigmentation
Promoter Regions, Genetic
Recombinant Proteins
Regulatory Sequences, Nucleic Acid
Retroelements
Transcription Factors
Transgenes

Source

Open in PubMed

Identifiers

PMID: 17994318
DOI: 10.1007/s00412-007-0132-6

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