Article
BRCA1 induces antioxidant gene expression and resistance to oxidative stress.
Cancer research - 1 Nov 2004
Bae Insoo, Fan Saijun, Meng Qinghui, Rih Jeong Keun, Kim Hee Jong, Kang Hyo Jin, Xu Jingwen, Goldberg Itzhak D, Jaiswal Anil K, Rosen Eliot M
Abstract excerpt
Mutations of the breast cancer susceptibility gene 1 (BRCA1), a tumor suppressor, confer an increased risk for breast, ovarian, and prostate cancers. To investigate the function of the BRCA1 gene, we performed DNA microarray and confirmatory reverse transcription-PCR analyses to identify BRCA1-re...
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