Article
The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations.
Brain : a journal of neurology - 1 Dec 2004
Ozawa Tetsutaro, Paviour Dominic, Quinn Niall P, Josephs Keith A, Sangha Hardev, Kilford Linda, Healy Daniel G, Wood Nick W, Lees Andrew J, Holton Janice L, Revesz Tamas
Abstract excerpt
Multiple system atrophy (MSA) has varying clinical (MSA-P versus MSA-C) and pathological [striatonigral degeneration (SND) versus olivopontocerebellar atrophy (OPCA)] phenotypes. To investigate the spectrum of clinicopathological correlations, we performed a semi-quantitative pathological analysis of 100 MSA cases with well-characterized clinical phenotypes. In 24 areas, chosen from both the striatonigral (StrN)...
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