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The Many Faces of Parkinsonism: Dissecting Clinical and Molecular Overlap in Multiple System Atrophy and Parkinson's Disease

2025-08-28

Abstract excerpt

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder with heterogeneous clinical manifestations, most commonly parkinsonism (MSA-P) or cerebellar ataxia (MSA-C). MSA-P shares many motor features with Parkinson’s disease (PD), including bradykinesia and rigidity, which often leads to misdiagnosis in early stages. However, disease trajectory, therapeutic responsiveness, and underlying pa...

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Literature Corpus work
bfd57fb5-1410-50be-a966-d2c7efb8080d
DOI
10.20944/preprints202508.2109.v1
Open publication

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