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Article

Adenylyl cyclase is dispensable for vegetative cell growth in the fission yeast Schizosaccharomyces pombe.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990

Maeda T, Mochizuki N, Yamamoto M

Abstract excerpt

Disruption of the cyr1 gene of Schizosaccharomyces pombe, which encodes adenylyl cyclase, did not confer lethality to fission yeast cells, although they grew 40% slower than wild-type strains in complete medium. These cells contained no measurable amount of cAMP and no adenylyl cyclase activity. When h+ and h- cyr1 disruptants were mixed, they underwent mating even in rich medium. Propagation of homothallic cyr1...

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Identifiers

PMID: 2172964
DOI: 10.1073/pnas.87.20.7814
PMCID: PMC54840

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Source receipt: pubmed, retrieved 7 Sept 2026.

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