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Associations between CYP11B2 gene -344T/C polymorphism and essential hypertension in the Han nationality in Shandong province.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2004

Sun Xiao-jian, Hou Xiao-fei, Liu Shao-rong, Liu Wen-bo, Tao Zhi-gang, Li Jian-yuan

Abstract excerpt

OBJECTIVE: To investigate whether the -344T/C polymorphism of CYP11B2 gene is associated with essential hypertension in the Hans in Shandong province. METHODS: Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured with radioimmunoassays; the hypertensives were classified as low-renin and normal- or high-renin group by PAC/PRA ratio. -344T/C polymorphism was determined by polymerase...

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PMID: 15505931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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