Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin.

Antimicrobial agents and chemotherapy - 1 Nov 2004

Li Xinying, Mariano Noriel, Rahal James J, Urban Carl M, Drlica Karl

Abstract excerpt

Stepwise selection of ciprofloxacin-resistant Haemophilus influenzae mutants produced first-, second-, third-, and fourth-step substitutions in GyrA (S84Y), ParC (S84R), GyrA (D88N), and ParC (E88K), respectively. Successive mutations raised the mutant selection window. The wild-type selection window for garenoxacin, levofloxacin, and moxifloxacin was also measured.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aza Compounds
Share to Ciprofloxacin
Share to DNA Topoisomerase IV

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haemophilus influenzae

Share to Levofloxacin

Share to Moxifloxacin

Share to Ofloxacin

Share to Quinolines

Source

Open in PubMed Open full text

Identifiers

PMID: 15504883
DOI: 10.1128/AAC.48.11.4460-4462.2004
PMCID: PMC525419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin.PMID 15504883Read ↗

Restricting the selection of antibiotic-resistant mutant bacteria: measurement and potential use of the mutant selection window.Semantic proximity Read ↗

Selection of moxifloxacin-resistant Staphylococcus aureus compared with five other fluoroquinolones.Semantic proximity Read ↗

Dose-related selection of fluoroquinolone-resistant Escherichia coli.Semantic proximity Read ↗

Relative potential for selection of quinolone-resistance-determining-region mutations in Streptococcus pneumoniae by gemifloxacin, gatifloxacin and moxifloxacin.Semantic proximity Read ↗

Molecular Characterization of Fluoroquinolone-Resistant Moraxella catarrhalis Variants Generated In Vitro by Stepwise Selection.Semantic proximity Read ↗

Evaluation of the mutant selection window for fluoroquinolones against Neisseria gonorrhoeae.Semantic proximity Read ↗

Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus.Semantic proximity Read ↗

Single- and multi-step resistance selection study of gemifloxacin compared with trovafloxacin, ciprofloxacin, gatifloxacin and moxifloxacin in Streptococcus pneumoniae.Semantic proximity Read ↗

In Vitro Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin.Semantic proximity Read ↗

Mutant prevention concentrations of levofloxacin, pazufloxacin and ciprofloxacin for A. baumannii and mutations in gyrA and parC genes.Semantic proximity Read ↗

Bacterial resistance studies using in vitro dynamic models: the predictive power of the mutant prevention and minimum inhibitory antibiotic concentrations.Semantic proximity Read ↗

Single and multi-step resistance selection study in Streptococcus pneumoniae comparing ceftriaxone with levofloxacin, gatifloxacin and moxifloxacin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.