Article
Selection of moxifloxacin-resistant Staphylococcus aureus compared with five other fluoroquinolones.
The Journal of antimicrobial chemotherapy - 1 Jun 2003
Griggs Deborah J, Marona Herida, Piddock Laura J V
Abstract excerpt
Fluoroquinolone-resistant mutants were selected from Staphylococcus aureus NCTC 8532 (F77), and two GrlA mutants of F77 (F193 and F194) with moxifloxacin, sparfloxacin, ofloxacin, grepafloxacin, levofloxacin and trovafloxacin. For mutants selected from F77, moxifloxacin, grepafloxacin and sparfloxacin selected preferentially for mutations in gyrA (Glu-88-->Lys). Ofloxacin and trovafloxacin selected most commonly...
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