Article
Evaluation of the mutant selection window for fluoroquinolones against Neisseria gonorrhoeae.
The Journal of antimicrobial chemotherapy - 1 Aug 2009
Allen George P, Hankins Cynthia D
Abstract excerpt
OBJECTIVES: The availability of antimicrobials that may be used for the treatment of infections caused by Neisseria gonorrhoeae has been limited by the emergence of antimicrobial resistance, particularly fluoroquinolone resistance. Few data exist regarding the pharmacodynamics of fluoroquinolone resistance selection in N. gonorrhoeae. METHODS: We used mutant prevention concentration (MPC) testing to define the...
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