Article
Identification of DLG5 and SLC22A5 gene polymorphisms in Malaysian patients with Crohn's disease.
Journal of digestive diseases - 1 Dec 2011
Chua Kek Heng, Lian Lay Hoong, Kee Boon Pin, Thum Chooi Mei, Lee Way Seah, Hilmi Ida, Goh Khean Lee
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the association of DLG5 and SLC22A5 gene polymorphisms with the onset of Crohn's disease (CD) in a Malaysian cohort. METHODS: Genomic DNA of 80 CD patients and 100 healthy unrelated control individuals was extracted and analyzed via polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) on DLG5 (4136 C/A), DLG5_e26 and SLC22A5 (-207 G/C)...
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