Article
Allelic loss of 14q32 in the pathogenesis of gastrointestinal and ampullary malignancies: mapping of the target region to a 17 cM interval.
Journal of cancer research and clinical oncology - 1 Feb 2005
Dai Yuan-Chang, Ho Chung-Liang, Tsai Yi-Chang, Hsu Yung-Hsiang, Chang Yu-Chuang, Liu Hsiao-Sheng, Chen Helen Hai-Wen, Chow Nan-Haw
Abstract excerpt
PURPOSE: The genetic basis for gastrointestinal and ampullary carcinomas remains uncertain. This study was performed to pinpoint novel chromosomal region involved in the tumorigenesis of gastrointestinal tract. METHODS: We screened the allelic status on 16 chromosomal arms in a patient with synchronous ampullary carcinoma and gastric cancer, but who had no family history of familial cancer syndrome. The...
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