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Article

Modulation of cardiac gap junction expression and arrhythmic susceptibility.

Circulation research - 12 Nov 2004

Danik Stephan B, Liu Fangyu, Zhang Jie, Suk H Jacqueline, Morley Gregory E, Fishman Glenn I, Gutstein David E

Abstract excerpt

Connexin43 (Cx43), the predominant ventricular gap junction protein, is critical for maintaining normal cardiac electrical conduction, and its absence in the mouse heart results in sudden arrhythmic death. The mechanisms linking reduced Cx43 abundance in the heart and inducibility of malignant ve...

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Identifiers

PMID: 15499029
DOI: 10.1161/01.RES.0000148664.33695.2a
PMCID: PMC2956442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15499029-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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