Article
In silico genetics: identification of a functional element regulating H2-Ealpha gene expression.
Science (New York, N.Y.) - 22 Oct 2004
Liao Guochun, Wang Jianmei, Guo Jingshu, Allard John, Cheng Janet, Ng Anh, Shafer Steve, Puech Anne, McPherson John D, Foernzler Dorothee, Peltz Gary, Usuka Jonathan
Abstract excerpt
Computational tools can markedly accelerate the rate at which murine genetic models can be analyzed. We developed a computational method for mapping phenotypic traits that vary among inbred strains onto haplotypic blocks. This method correctly predicted the genetic basis for strain-specific diffe...
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