Article

Analysis of Inbred Mouse strains’ High-Impact Genotype-phenotype Hypotheses (AIMHIGH) reveals novel disease-causing candidate genes

2022-08-07

Abstract excerpt

Inbred mouse strains reveal the molecular basis of mammalian traits and diseases, particularly recessive ones. We utilized mouse community curated resources to set up an automated screen to discover novel testable gene function hypotheses. Using 11,832 community contributed strain-differentiating experiments and trait presence/absence scoring, we searched for all experiments where strains can be split by their phe...

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Literature Corpus work: 15e9cbdd-a328-5f32-a39e-2e127edea0ec
DOI: 10.1101/2022.08.07.503105

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