Article
IFN-gamma gene polymorphisms associate with development of EBV+ lymphoproliferative disease in hu PBL-SCID mice.
Blood - 15 Feb 2005
Dierksheide Julie E, Baiocchi Robert A, Ferketich Amy K, Roychowdhury Sameek, Pelletier Ronald P, Eisenbeis Charles F, Caligiuri Michael A, VanBuskirk Anne M
Abstract excerpt
Posttransplantation lymphoproliferative disorder (PTLD) is a devastating post-transplantation complication often associated with Epstein-Barr virus (EBV). Although the type and length of immunosuppression are risk factors, a patient's inherent immune capacity also likely contributes to this disorder. This report uses severe-combined immunodeficient mice given injections of human peripheral blood leukocytes (hu...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
