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Article

IFN gamma gene polymorphism may contribute to the susceptibility to CLL.

Pathology oncology research : POR - 1 Jun 2010

Urbanowicz Iwona, Mazur Grzegorz, Stacherzak-Pawlik Jolanta, Bogunia-Kubik Katarzyna, Wróbel Tomasz, Woźniak Mieczysław, Kuliczkowski Kazimierz

Abstract excerpt

The pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL) has been linked with the production and activity of certain growth factors. However a significant proportion of CLL patients display immune abnormalities suggestive of aberrant cytokine secretion and/or response. In contrast to B lymphocytes, T cells of B-CLL patients characterise with the increased production of interferon-gamma (IFN-gamma) and this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 19757192
DOI: 10.1007/s12253-009-9209-2

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IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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