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Article

Sequencing of isolated sperm cells for direct haplotyping of a human genome.

Genome research - 1 May 2013

Kirkness Ewen F, Grindberg Rashel V, Yee-Greenbaum Joyclyn, Marshall Christian R, Scherer Stephen W, Lasken Roger S, Venter J Craig

Abstract excerpt

There is increasing evidence that the phenotypic effects of genomic sequence variants are best understood in terms of variant haplotypes rather than as isolated polymorphisms. Haplotype analysis is also critically important for uncovering population histories and for the study of evolutionary genetics. Although the sequencing of individual human genomes to reveal personal collections of sequence variants is now...

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Identifiers

PMID: 23282328
DOI: 10.1101/gr.144600.112
PMCID: PMC3638138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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