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Linear allele-specific long-range amplification: a novel method of long-range molecular haplotyping.

Human mutation - 1 Oct 2005

Wu Wei-Ming, Tsai Hsiang-Ju, Pang Jong-Hwei S, Wang Tzu-Hao, Wang Hsin-Shih, Hong Hong-Shang, Lee Yun-Shien

Abstract excerpt

Haplotypes have been repeatedly shown to be more powerful than collections of single-locus markers in gene-mapping studies. Various haplotyping methods including statistical estimation are employed but molecular haplotyping, the acquisition of information directly on physical DNA sequences, has been in demand for its accuracy and independence from family pedigrees. We investigated the allelic specificity of...

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PMID: 16134125
DOI: 10.1002/humu.9369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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