Article
An efficient method for multi-locus molecular haplotyping.
Nucleic acids research - 1 Jan 2007
Konfortov Bernard A, Bankier Alan T, Dear Paul H
Abstract excerpt
Many methods exist for genotyping--revealing which alleles an individual carries at different genetic loci. A harder problem is haplotyping--determining which alleles lie on each of the two homologous chromosomes in a diploid individual. Conventional approaches to haplotyping require the use of several generations to reconstruct haplotypes within a pedigree, or use statistical methods to estimate the prevalence...
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