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Article

Molecular mechanisms in thrombotic thrombocytopenic purpura.

Seminars in thrombosis and hemostasis - 1 Oct 2004

Tsai Han-Mou

Abstract excerpt

Thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia and microangiopathic hemolysis. Unlike the typical hemolytic uremic syndrome (HUS), which follows infection with shiga toxin-producing microorganisms, most cases of TTP do not have an obvious etiology. Recent studies revealed that a plasma zinc metalloprotease ADAMTS (a disintegrin and metalloprotease with thrombospondin type 1 motif)...

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Topics

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Share to ADAM Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cloning, Molecular

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Share to Purpura, Thrombotic Thrombocytopenic

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Source

Identifiers

PMID: 15497097
DOI: 10.1055/s-2004-835675

Genes

ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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