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Article

ADAMTS13 and TTP.

Current opinion in hematology - 1 Sept 2002

Zheng Xinglong, Majerus Elaine M, Sadler J Evan

Abstract excerpt

Thrombotic thrombocytopenic purpura (TTP) has been a mysterious and deadly disease that often could be treated effectively by plasma exchange, but without real understanding of the underlying pathophysiology. Recent advances now suggest that deficiency of a specific von Willebrand factor (VWF) cleaving protease promotes tissue injury in TTP. VWF multimers participate in the formation of platelet thrombi....

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Source

Identifiers

PMID: 12172456
DOI: 10.1097/00062752-200209000-00001

Genes

ADAMTS13
VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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