Article
Thrombotic thrombocytopenic purpura.
Blood - 25 May 2017
Joly Bérangère S, Coppo Paul, Veyradier Agnès
Abstract excerpt
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi. TTP is specifically related to a severe deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13), the specific...
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