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Article

Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach.

Human molecular genetics - 15 Dec 2004

Jinnai Nobuyoshi, Sakagami Takuro, Sekigawa Takashi, Kakihara Miho, Nakajima Toshiaki, Yoshida Kenichi, Goto Shin, Hasegawa Takashi, Koshino Takeshi, Hasegawa Yoshinori, Inoue Hiromasa, Suzuki Naohito, Sano Yasuyuki, Inoue Ituro

Abstract excerpt

Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs inhibit the cyclooxygenase pathway, leading to enhancement of the lipoxygenase pathway. We evaluated allelic association of 370 single nucleotide polymorphisms (SNPs) of 63 candidate genes, mostly from the arachidonic acid metabolic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15496426
DOI: 10.1093/hmg/ddh332

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STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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