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Article

Association analysis of formyl peptide receptor 2 (FPR2) polymorphisms and aspirin exacerbated respiratory diseases.

Journal of human genetics - 1 Apr 2012

Kim Hee-Jeong, Cho Sung-Hwan, Park Jong-Sook, Lee Tae-Hyeong, Lee Eun-Ju, Kim Yong-Hoon, Uh Soo-Taek, Chung Il Yup, Kim Mi-Kyeong, Choi Inseon S, Park Byung-Lae, Shin Hyoung-Doo, Park Choon-Sik

Abstract excerpt

Aspirin-exacerbated respiratory diseases (AERD) are associated with the metabolism of arachidonic acid. FPR2 (formyl peptide receptor2) is a high-affinity ligand receptor for potent anti-inflammatory lipid metabolites: lipoxins. Thus, functional alterations of the FPR2 may contribute to AERD. We investigated the relationship between single-nucleotide polymorphisms (SNPs) in the FPR2 and AERD. Asthmatics were...

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Source

Identifiers

PMID: 22377711
DOI: 10.1038/jhg.2012.12

Genes

FPR2
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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