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Article

eNOS T-786C polymorphism affects atorvastatin-induced changes in erythrocyte membrane fluidity.

European journal of clinical pharmacology - 1 Apr 2009

Nagassaki S, Herculano R D, Graeff C F O, Tanus-Santos J E

Abstract excerpt

PURPOSE: Statins have pleiotropic effects, including endothelial nitric oxide synthase (eNOS) upregulation and increased nitric oxide formation, which can be modulated by a genetic polymorphism in the promoter region of the eNOS gene (T-786C). Here, we report our investigation of whether this polymorphism modulates the effects of atorvastatin on the fluidity of erythrocyte membranes. METHODS: We genotyped 200...

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Identifiers

PMID: 19104789
DOI: 10.1007/s00228-008-0602-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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