Article
Simvastatin treatment increases nitrite levels in obese women: modulation by T(-786)C polymorphism of eNOS.
Nitric oxide : biology and chemistry - 1 Sept 2013
Andrade V L, Sertório J T C, Eleuterio N M, Tanus-Santos J E, Fernandes K S, Sandrim V C
Abstract excerpt
OBJECTIVE AND SUBJECTS: Evidence indicates an impairment of nitric oxide (NO) in obesity. Statins present pleiotropic effects independently of cholesterol-lowering, including increasing of eNOS expression and antioxidant effects. We evaluated the effects of simvastatin treatment at 45 days on cir...
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