Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Study on the mutation of human telomeric repeat binding factor 1 gene in malignant hematopoietic cell lines].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2004

Sun Jie, Huang He, Zhu Yuan-yuan

Abstract excerpt

OBJECTIVE: To detect mutations of human telomeric repeat binding factor 1 (TERF1) gene in 11 malignant hematopoietic cell lines, which have positive telomerase activity, and evaluate the significance of the mutations. METHODS: Genome structure of TERF1 was predicted by using biology information program, and verified by PCR and sequencing. Telomerase activity was detected by telomeric repeat amplification...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematologic Neoplasms
Share to HL-60 Cells
Share to Jurkat Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to K562 Cells

Share to Shelterin Complex

Share to Telomerase

Share to Telomere-Binding Proteins

Share to U937 Cells

Source

Identifiers

PMID: 15182533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Study on the mutation of human telomeric repeat binding factor 1 gene in malignant hematopoietic cell lines].PMID 15182533Read ↗

Study on the expression and mutation of human telomeric repeat binding factor (hTRF1) in 10 malignant hematopoietic cell lines.Semantic proximity Read ↗

[Localization of human telomere repeat binding factor 1 in telomerase-positive and-negative cells and its expression during cell cycle].Semantic proximity Read ↗

Detecting the polymorphism of TERF1 gene by an improved PCR-RFLP method.Semantic proximity Read ↗

[Telomere length measurement of 10 Chinese patients with bone marrow failure syndrome.].Semantic proximity Read ↗

[Study on telomerase gene mutation in northern Chinese patients with acquired bone marrow failure syndromes.].Semantic proximity Read ↗

Association of newly identified genetic variant rs2853677 of TERT with non-small cell lung cancer and leukemia in population of Jammu and Kashmir, IndiaSemantic proximity Read ↗

Telomerase gene mutation screening in Chinese patients with aplastic anemia.Semantic proximity Read ↗

Identification and functional characterization of novel telomerase variant alleles in Japanese patients with bone-marrow failure syndromes.Semantic proximity Read ↗

Novel telomerase reverse transcriptase gene mutation in a family with aplastic anaemia.Semantic proximity Read ↗

Genetic variation in telomeric repeat binding factors 1 and 2 in aplastic anemia.Semantic proximity Read ↗

[Mutation of GSTT-1 gene in MDS patients and its clinical application].Semantic proximity Read ↗

Differential gene expression of human telomerase-associated protein hTERT and TEP1 in human hematopoietic cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.