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[The relationship between paraoxanase gene Leu-Met (55) and Gln-Arg (192) polymorphisms and coronary artery disease].

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir - 1 Oct 2009

Taşkiran Pinar, Cam Sirri F, Sekuri Cevat, Tüzün Nurullah, Alioğlu Emin, Altintaş Nuray, Berdeli Afig

Abstract excerpt

OBJECTIVES: Paraoxonase (PON1) is a high-density lipoprotein (HDL)-associated esterase that hydrolyses lipoperoxides. PON1 serves as a protective factor against oxidative modification of LDL, suggesting that it may play an important role in the prevention of atherosclerotic process. Research has focused on two polymorphisms: leucine (L allele) to methionine (M allele) substitution at codon 55, and glutamine (A...

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Source

Identifiers

PMID: 20098041

Genes

CAD
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[The relationship between paraoxanase gene Leu-Met (55) and Gln-Arg (192) polymorphisms and coronary artery disease].PMID 20098041Read ↗

Paraoxonase Gln-Arg(192) and Leu-Met(55) gene polymorphisms and enzyme activity in a population with a low rate of coronary heart disease.Semantic proximity Read ↗

[Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease].Semantic proximity Read ↗

A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.Semantic proximity Read ↗

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Human paraoxonase 1 gene polymorphisms and the risk of coronary heart disease: a community-based study.Semantic proximity Read ↗

Paraoxonase 1 gene polymorphisms and enzyme activities in coronary artery disease and its relationship to serum lipids and glycemia.Semantic proximity Read ↗

[Study of the association between paraoxonase1 55 Met/Leu, paraoxonase2 148 Ala/Gly and manganese superoxide dismutase (MnSOD) 9 Ala/Val genetic polymorphisms and coronary heart disease].Semantic proximity Read ↗

Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.Semantic proximity Read ↗

Relationship of age-related myocardial infarction risk and Gln/Arg 192 variants of the human paraoxonase1 gene: the REGICOR study.Semantic proximity Read ↗

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Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.Semantic proximity Read ↗

Paraoxonase1 polymorphism Leu-Met55 is associated with cerebral infarction in Japanese population.Semantic proximity Read ↗

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