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Article

Identification of a region in the vitamin D-binding protein that mediates its C5a chemotactic cofactor function.

The Journal of biological chemistry - 17 Dec 2004

Zhang Jianhua, Kew Richard R

Abstract excerpt

The vitamin D-binding protein (DBP), also known as group-specific component or Gc-globulin, is a multifunctional plasma protein that can significantly enhance the leukocyte chemotactic activity to C5a and C5a des-Arg. DBP is a member of the albumin gene family and has a triple domain modular structure with extensive disulfide bonding that is characteristic of this protein family. The goal of this study was to...

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Source

Identifiers

PMID: 15485893
DOI: 10.1074/jbc.M411462200

Genes

DBP
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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