Article
Gc protein (vitamin D-binding protein): Gc genotyping and GcMAF precursor activity.
Anticancer research - 1 Jan 2000
Nagasawa Hideko, Uto Yoshihiro, Sasaki Hideyuki, Okamura Natsuko, Murakami Aya, Kubo Shinichi, Kirk Kenneth L, Hori Hitoshi
Abstract excerpt
The Gc protein (human group-specific component (Gc), a vitamin D-binding protein or Gc globulin), has important physiological functions that include involvement in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5a for neutrophils in inflammation and macrophage activation (mediated by a GalNAc-modified Gc protein (GcMAF)). In this review, the...
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