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Article

Regulation of Bin1 SH3 domain binding by phosphoinositides.

The EMBO journal - 10 Nov 2004

Kojima Chie, Hashimoto Ari, Yabuta Izumi, Hirose Mayumi, Hashimoto Shigeru, Kanaho Yasunori, Sumimoto Hideki, Ikegami Takahisa, Sabe Hisataka

Abstract excerpt

Bin1/M-amphiphysin-II is an amphiphysin-II isoform highly expressed in transverse tubules of adult striated muscle and is implicated in their biogenesis. Bin1 contains a basic unique amino-acid sequence, Exon10, which interacts with certain phosphoinositides such as phosphatidylinositol-4,5-bisphosphate (PI(4,5)P(2)), to localize to membranes. Here we found that Exon10 also binds to the src homology 3 (SH3)...

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Identifiers

PMID: 15483625
DOI: 10.1038/sj.emboj.7600442
PMCID: PMC526460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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