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Article

Amphiphysin-2 (BIN1) functions and defects in cardiac and skeletal muscle.

Trends in molecular medicine - 1 Jun 2024

Giraud Quentin, Laporte Jocelyn

Abstract excerpt

Amphiphysin-2 is a ubiquitously expressed protein also known as bridging integrator 1 (BIN1), playing a critical role in membrane remodeling, trafficking, and cytoskeleton dynamics in a wide range of tissues. Mutations in the gene encoding BIN1 cause centronuclear myopathies (CNM), and recent evidence has implicated BIN1 in heart failure, underlining its crucial role in both skeletal and cardiac muscle....

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Identifiers

PMID: 38514365
DOI: 10.1016/j.molmed.2024.02.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Amphiphysin-2 (BIN1) functions and defects in cardiac and skeletal muscle.PMID 38514365Read ↗

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