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Article

Liver cell transplantation leads to repopulation and functional correction in a mouse model of Wilson's disease

8 Oct 2004

Abstract excerpt

BACKGROUND AND AIM: The toxic milk (tx) mouse is a non-fatal animal model for the metabolic liver disorder, Wilson's disease. The tx mouse has a mutated gene for a copper-transporting protein, causing early copper accumulation in the liver and late accumulation in other tissues. The present study investigated the efficacy of liver cell transplantation (LCT) to correct the tx mouse phenotype. METHODS: Congenic...

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Identifiers

PMID: 15482536
DOI: 10.1111/j.1440-1746.2004.03451.x

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