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Article

The development and characterization of an in vitro model of psoriasis.

The Journal of investigative dermatology - 1 Nov 2004

Barker Carol L, McHale Mark T, Gillies Angela K, Waller John, Pearce David M, Osborne Joy, Hutchinson Peter E, Smith Gill M, Pringle James H

Abstract excerpt

In this study, the phenotype of psoriatic keratinocytes and fibroblasts in reconstructed skin models was compared to those constructed from normal cells. Characterization of this model by immunohistochemistry showed that classical markers of keratinocyte differentiation exhibited similar patterns of distribution in the psoriatic models to those derived from normal cells and generally reflected in vivo...

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Source

Identifiers

PMID: 15482477
DOI: 10.1111/j.0022-202X.2004.23435.x

Genes

CXCR2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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