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Article

Identifying targets for topical RNAi therapeutics in psoriasis: assessment of a new in vitro psoriasis model.

Archives of dermatological research - 1 Aug 2013

Bracke S, Desmet E, Guerrero-Aspizua S, Tjabringa S G, Schalkwijk J, Van Gele M, Carretero M, Lambert J

Abstract excerpt

Diseases of the skin are amenable to RNAi-based therapies and targeting key components in the pathophysiology of psoriasis using RNAi may represent a successful new therapeutic strategy. We aimed to develop a straightforward and highly reproducible in vitro psoriasis model useful to study the effects of gene knockdown by RNAi and to identify new targets for topical RNAi therapeutics. We evaluated the use of...

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Source

Identifiers

PMID: 23775225
DOI: 10.1007/s00403-013-1379-9

Genes

CAMP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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