Article
Variation analysis of beta3-adrenergic receptor and melanocortin-4 receptor genes in childhood obesity.
Pediatrics international : official journal of the Japan Pediatric Society - 1 Apr 2007
Kinoshita Tomoe, Hanaki Keiichi, Nagaishi Jun-Ichi, Kawashima Yuki, Adachi Kaori, Nanba Eiji, Kanzaki Susumu
Abstract excerpt
BACKGROUND: Decreased energy expenditure and increased food intake are principal causes for obesity. In the present study, genotypes of beta(3)-adrenergic receptor (beta(3)AR) and of melanocortin-4 receptor (MC4R), both of which are believed to have a close link to the cause of obesity, were analyzed and compared with phenotypes of childhood obesity. METHODS: Thirty-five obese children with moderate to severe...
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