Article
Identification of a deletion variant in the gene encoding the human alpha(2A)-adrenergic receptor.
European journal of endocrinology - 1 Mar 2001
Hamann A, Brieske C, Tafel J, Buttron P, Schwarzloh B, Münzberg H, Hinney A, Mayer H, Siegfried W, Hebebrand J, Greten H, Algenstaedt P, Ziegler R
Abstract excerpt
OBJECTIVE: The alpha(2)-adrenergic receptors are involved in the effects of catecholamines on energy metabolism. Of three known subtypes with differential expression, alpha(2A)-adrenergic receptors are also localized in adipose tissue where they counteract the lipolytic activity of beta-adrenergic receptors. This study was undertaken to assess whether variants in the alpha(2A)-adrenergic receptor gene are...
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