Article
Lack of association between polymorphism in the beta2-adrenergic receptor gene, hypertension, and obesity in the Olivetti heart study.
American journal of hypertension - 1 Aug 2004
Galletti Ferruccio, Iacone Roberto, Ragone Eliana, Russo Ornella, Della Valle Elisabetta, Siani Alfonso, Barba Gianvincenzo, Farinaro Eduardo, Strazzullo Viviana, Strazzullo Pasquale
Abstract excerpt
OBJECTIVE: Several case-control studies have explored the possible association between polymorphism in the beta2 adrenoreceptor gene (beta2AR), hypertension, and obesity--the focus being in particular on the Arg16Gly and Gln27Glu substitutions, which appear to modify the extracellular part of the beta2AR with possible functional modification. However, controversial results have been obtained. DESIGN AND METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.