Article
Amplified fragment length polymorphism measures proportions of malaria parasites carrying specific alleles in complex genetic mixtures.
Molecular and biochemical parasitology - 1 Aug 2004
Martinelli Axel, Hunt Paul, Cheesman Sandra J, Carter Richard
Abstract excerpt
We are interested in developing a method for the identification of those genes in malaria parasites which underlie a variety of selectable phenotypes of the parasites including drug resistance and strain-specific immunity. A key aspect of our approach is to subject a genetically mixed population of malaria parasites to a specific phenotypic selection pressure such as the administration of an antimalarial drug and...
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