Population genetics and the detection of immunogenic and drug-resistant loci in Plasmodium.

Abstract excerpt

Host immunity will result in increased homozygosity at immunogenic loci if they encode products that elicit allele-specific immune responses. This increased homozygosity can be detected by comparison to 'neutral' (i.e. unselected) loci in the same genome which act as controls for the various epidemiological factors, such as biting rate, which affect homozygosity. Numerical results suggest that homozygosity should...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Antigens, Protozoan
• Share to Drug Resistance