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Are Plasmodium falciparum parasites present in peripheral blood genetically the same as those sequestered in the tissues?

The American journal of tropical medicine and hygiene - 1 May 2006

Dembo Edson G, Phiri Happy T, Montgomery Jacqui, Molyneux Malcolm E, Rogerson Stephen J

Abstract excerpt

Since quinine does not inhibit the growth of Plasmodium falciparum ring stages or mature schizonts, parasites may continue to emerge from sequestration sites after starting treatment. We used polymerase chain reaction amplification of P. falciparum merozoite surface protein 1 (MSP-1) and MSP-2 alleles to distinguish genotypes infecting 58 children with severe malaria. To examine changes in parasite populations in...

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PMID: 16687670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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