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Article

Specific binding of a basic peptide from HIV-1 Rev.

The EMBO journal - 1 Mar 1992

Kjems J, Calnan B J, Frankel A D, Sharp P A

Abstract excerpt

Human immunodeficiency virus type I (HIV-1) encodes a regulatory protein, Rev, which is required for cytoplasmic expression of incompletely spliced viral mRNA. Rev activity is mediated through specific binding to a cis-acting Rev responsive element (RRE) located within the env region of HIV-1. A monomer Rev binding site corresponding to 37 nucleotides of the RRE (IIB RNA) was studied by RNA footprinting,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1547776
DOI: 10.1002/j.1460-2075.1992.tb05152.x
PMCID: PMC556554

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Source receipt: pubmed, retrieved 7 Sept 2026.

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