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Article

Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves.

The Journal of heart valve disease - 1 Sept 2004

Rabkin-Aikawa Elena, Farber Mark, Aikawa Masanori, Schoen Frederick J

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: The roles of cardiac valvular interstitial cells (VIC) in extracellular matrix remodeling in fetal development, adaptation and response to injury are largely unknown. METHODS: The phenotype of VIC was studied in health (normal adult human and sheep), development (fetal human and sheep), disease (human mitral valves with myxomatous degeneration), adaptation (clinical pulmonary to...

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Identifiers

PMID: 15473488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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