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Article

Interstitial cells from dogs with naturally occurring myxomatous mitral valve disease undergo phenotype transformation.

The Journal of heart valve disease - 1 Jul 2008

Disatian Sirilak, Ehrhart E J, Zimmerman Sarah, Orton E Christopher

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: Myxomatous mitral valve disease is a common naturally occurring heart disease of dogs that is pathologically similar to myxomatous mitral valve disease in humans. It was hypothesized that interstitial cell phenotype transformation recently described in human myxomatous valves might also occur in dogs with myxomatous mitral valves, and correlate with disease severity. METHODS:...

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PMID: 18751470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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