Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Oct 2004

Zar H J, Alvarez-Martinez M J, Harrison A, Meshnick S R

Abstract excerpt

BACKGROUND: Pneumocystis jiroveci (formerly Pneumocystis carinii) pneumonia (PCP) is a major cause of mortality in human immunodeficiency virus (HIV)-infected infants in Africa, but the prevalence of mutations in the gene encoding dihydropteroate synthase (DHPS) in isolates from Africa has not been reported. METHODS: This study investigated the prevalence of DHPS mutations in P. jiroveci isolates from South...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS-Related Opportunistic Infections
Share to Dihydropteroate Synthase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Mutation

Share to Pneumocystis carinii

Share to Pneumonia, Pneumocystis

Share to South Africa

Share to Trimethoprim, Sulfamethoxazole Drug Combination

Source

Identifiers

PMID: 15472859
DOI: 10.1086/424010

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumonia.PMID 15472859Read ↗

Dihydropteroate synthase and novel dihydrofolate reductase gene mutations in strains of Pneumocystis jirovecii from South Africa.Semantic proximity Read ↗

Low Prevalence of Pneumocystis pneumonia (PCP) but High Prevalence of Pneumocystis dihydropteroate synthase (dhps) Gene Mutations in HIV-Infected Persons in UgandaSemantic proximity Read ↗

Pneumocystis jirovecii dihydropteroate synthase (DHPS) genotypes in non-HIV-immunocompromised patients: a tertiary care reference health centre study.Semantic proximity Read ↗

Dihydropteroate synthase (DHPS) gene mutation study in HIV-Infected Indian patients with Pneumocystis jirovecii pneumonia.Semantic proximity Read ↗

Low prevalence of DHFR and DHPS mutations in Pneumocystis jirovecii strains obtained from a German cohort.Semantic proximity Read ↗

[Dihydropteroate Synthase (DHPS) Gene Mutations and Mitochondrial Large Subunit (mtLSU) rRNA Genotype Variations in Pneumocystis jirovecii Strains].Semantic proximity Read ↗

Evaluation of the PneumoGenius® PCR assay for the diagnosis of Pneumocystis pneumonia and the detection of Pneumocystis dihydropteroate synthase mutations in respiratory samples.Semantic proximity Read ↗

Study of dihydropteroate synthase (DHPS) gene mutations among isolates of Pneumocystis jiroveci.Semantic proximity Read ↗

Clinical significance of mutations in dihydropteroate synthase in Pneumocystis jirovecii pneumonia among non-HIV-infected patients.Semantic proximity Read ↗

Molecular Analysis of Dihydropteroate Synthase Gene Mutations in Pneumocystis jirovecii Isolates among Bulgarian Patients with Pneumocystis Pneumonia.Semantic proximity Read ↗

Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance.Semantic proximity Read ↗

Genetic polymorphisms associated with treatment failure and mortality in pediatric PneumocystosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.