Article
Distinctive genetic features exhibited by the Y-family DNA polymerases in Bacillus subtilis.
Molecular microbiology - 1 Oct 2004
Duigou Stéphane, Ehrlich S Dusko, Noirot Philippe, Noirot-Gros Marie-Françoise
Abstract excerpt
Translesional DNA polymerases form a large family of structurally related proteins, known as the Y-polymerases. Bacillus subtilis encodes two Y-polymerases, referred herewith as Pol Y1 and Pol Y2. Pol Y1 was expressed constitutively and did not mediate UV mutagenesis. Pol Y1 overexpression increased spontaneous mutagenesis. This effect depended on Pol Y1 polymerase activity, Pol Y1 interaction with the...
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