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Article

Phosphorylation of Artemis following irradiation‐induced DNA damage

5 Oct 2004

Abstract excerpt

Artemis is a DNA repair factor required for V(D)J recombination, repair of DNA damage induced by ionizing radiation (IR) or radiomimetic drugs, and the maintenance of genome integrity. During V(D)J recombination, Artemis participates in the resolution of hairpin-sealed coding ends, a step crucial to the constitution of the gene encoding for the antigen receptor of lymphocytes. The precise role of Artemis in the...

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PMID: 15468306
DOI: 10.1002/eji.200425455

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