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Article

NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer.

Oncogene - 11 Nov 2004

Dai Jia Le, Wang Lei, Sahin Aysegul A, Broemeling Lyle D, Schutte Mieke, Pan Yong

Abstract excerpt

Yeast two-hybrid screening was used to explore novel proteins that interact with a breast tumor or metastasis suppressor, SYK (spleen tyrosine kinase). The screening yielded NHERF (Na+/H+ exchanger regulatory factor, also known as NHERF1 or EBP-50) that binds to the interdomain B of SYK. NHERF is...

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Source

Identifiers

PMID: 15467753
DOI: 10.1038/sj.onc.1207962

Genes

SYK
EBP
NHERF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15467753-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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